Reclaim your Balance

In 1996, Giovane Medical, founded by Dr. Zuccolotto, began providing hormone replacement therapy for men and women. Their treatments relied on advanced blood testing to ensure personalized care. Approximately 15 years after the FDA approval of Propecia (Finasteride) for hair loss, around 2010, Dr. Troy Cashatt, MD, and Dr. Zuccolotto observed a recurring pattern in men taking Finasteride who were experiencing symptoms of low testosterone.

The blood tests from these men consistently revealed two critical issues:

• Elevated estrogen levels

• Low free testosterone

As more patients with similar symptoms came to Giovane Medical, it became apparent—and later verified by external clinical evidence—that a potential side effect of Finasteride was its impact on hormone levels: increased estrogen and decreased free testosterone. (See Finasteride Side Effects for more details.)

In 2020, inspired by cardiologists who recommended CoQ10 supplements alongside statin medications to counteract statin-induced mitochondrial depletion (see the Statins and CoQ10 story), Dr. Zuccolotto, set out to achieve a similar goal. He wanted to create a natural supplement that would support men taking 5-alpha reductase inhibitors like Propecia, Finasteride, or Dutasteride for hair loss and achieve a similar success with supplements that would naturally help stabilize Estrogen and the Free testosterone.

The objective was clear: Develop a safe and effective supplement to stabilize estrogen levels and increase free testosterone.

In February 2023, Dr. Zuccolotto, began independently consulting with supplement experts, suppliers, and hair loss industry leaders such as Dr. Craig Ziering to design the perfect formulation. After extensive research and testing, the collective result finalized what was determined to be the optimal combination of ingredients and dosages to achieve this goal. This formulation, now known as Alpha Balance, was designed to naturally support hormonal balance.

Dr. Zuccolotto, employed Giovane Medical to conduct a rigorous in-house clinical trial to evaluate Alpha Balance’s effectiveness. They recruited men aged 25 to 55 who had been taking daily oral Finasteride or Dutasteride for at least one year.

1. Participants’ blood work was tested before starting the supplement to measure free testosterone and estradiol (estrogen) levels.

2. Each participant took Alpha Balance daily, alongside their hair loss medication, for 60 days.

3. After 60 days, blood work was retested to evaluate changes in free testosterone and estrogen levels.

Results: The study confirmed the expected hormonal imbalances in the initial bloodwork: elevated estrogen and low free testosterone. After 60 days of taking Alpha Balance, participants demonstrated significant improvements in:

• Stabilizing estrogen levels

• Increasing free testosterone levels

Some participants experienced remarkable results, showcasing Alpha Balance’s ability to support hormonal health effectively.

While researching Finasteride’s side effects, Giovane Medical discovered a similar hormonal imbalance in men who frequently use THC, either inhaled or ingested. Clinical evidence suggests that regular THC use can lead to:

• Lower sperm counts

• Elevated estrogen levels

• Decreased free testosterone levels

Recognizing this, Dr. Zuccolotto, also recommends Alpha Balance for men who use THC regularly, providing a broader application for the supplement’s hormonal support.

Alpha Balance represents the culmination of decades of medical expertise and innovation. Designed specifically for men facing hormonal imbalances from medications like Finasteride or lifestyle factors like THC use, this supplement provides a natural, effective solution to restore balance and confidence.

With a commitment to safety, efficacy, and clinical validation, Dr. Zuccolotto, continues to lead the way in hormonal health.

Role and Benefits:

• Support for Estrogen Metabolism:

• Mechanism: Hesperetin works in tandem with DIM to promote the efficient breakdown and elimination of estrogen from the body.

• Impact: This dual action ensures a more effective reduction of estrogen dominance, supporting hormonal harmony.

• Antioxidant and Anti-Inflammatory Properties:

• Mechanism: Hesperetin is a potent flavonoid that combats oxidative stress and reduces inflammation at the cellular level.

• Impact: These properties contribute to overall hormonal and cellular health, protecting against chronic inflammation-related conditions.

Combinatorial Benefits:

• The antioxidant effects of Hesperetin complement DIM 's hormonal  regulation, creating a protective environment that supports both  hormonal balance and cellular integrity. This combination enhances the  overall efficacy of the formulation in maintaining long-term health.

Role and Benefits:

• Boosts Testosterone Levels 

• Mechanism:  Fenugreek inhibits aromatase activity, the enzyme responsible for converting testosterone into estrogen.

• Impact:  By  reducing the conversion rate, Fenugreek helps increase and maintain  higher testosterone levels, supporting muscle growth, libido, and  energy.

• Improves Libido and Energy Levels: 

• Mechanism:  Fenugreek contains compounds that stimulate androgen receptors, enhancing sexual desire and overall vitality. 

• Impact: This leads to improved sexual function and increased physical performance.

• Metabolic Health and Male Vitality:

• Mechanism: Fenugreek  supports healthy blood sugar levels and metabolic function, reducing  the risk of insulin resistance and promoting sustained energy.

• Impact: Enhanced metabolic health contributes to overall male vitality and reduces fatigue.

Combinatorial Benefits:

• Fenugreek's ability to boost testosterone complements DIM and  Hesperetin's estrogen regulating functions, ensuring that testosterone  levels remain elevated while estrogen levels are kept in check. This  synergy maximizes hormonal balance and supports comprehensive male  health. 

Role and Benefits:

• Supports Hair Health:

• Mechanism: Biotin, also known as Vitamin B7, plays a crucial role in the synthesis of keratin, a key structural protein in hair.

• Impact: Adequate  biotin levels promote stronger, healthier hair growth, addressing hair  loss concerns associated with hormonal imbalances.

• Promotes Healthy Nails and Skin:

• Mechanism: Biotin enhances the growth and strength of nails and improves skin health by supporting cellular growth and regeneration.

• Impact: This leads to reduced brittleness of nails and improved skin texture and appearance.

Combinatorial Benefits:

• Biotin's role in supporting hair health complements DIM's  estrogen-regulating effects, providing a multi-faceted approach to  preventing hair loss and promoting overall hair vitality. This  combination ensures that hormonal balance directly translates into  tangible improvements in physical appearance and self-confidence. 

Role and Benefits:

• Enhanced Nutrient Bioavailability:

• Mechanism: BioPerine,  a patented extract of piperine from black pepper, significantly  increases the absorption and bioavailability of other nutrients in the  formulation.

• Impact: By  enhancing the uptake of DIM, Fenugreek, and other active compounds,  BioPerine ensures that their benefits are maximized, leading to more  effective results.

• Improves Overall Supplement Efficacy:

• Mechanism: BioPerine  inhibits certain enzymes that can metabolize nutrients too quickly,  allowing for prolonged and enhanced activity of the active ingredients.

• Impact: This  leads to sustained therapeutic levels of the supplements, ensuring  continuous support for hormonal balance and overall health.

Combinatorial Benefits:

• BioPerine acts as a bioavailability enhancer, amplifying the  effects of DIM, Fenugreek, Hesperetin, and Biotin. This synergistic  interaction ensures that each ingredient performs at its highest  potential, making the entire formulation more effective in supporting  hormonal balance, metabolic health, and overall male vitality.

The proprietary formulation of Alpha Balance  leverages the synergistic interactions between its key ingredients to  provide comprehensive support for hormonal balance and male health:

• Synergistic Hormonal Regulation: DIM  and Hesperetin work together to enhance estrogen metabolism and  maintain a balanced estrogen-to-testosterone ratio, while Fenugreek  boosts testosterone levels and reduces its conversion to estrogen . This  multipronged approach ensures optimal hormonal harmony.

• Maximized Nutrient Absorption: BioPerine  enhances the bioavailability of DIM, Fenugreek, Hesperetin, and Biotin,  ensuring that each nutrient is effectively absorbed and utilized by the  body. This leads to more pronounced and sustained health benefits.

• Comprehensive Health Support: Beyond  hormonal balance, the formulation supports muscle performance,  metabolic health, cardiovascular function, and hair health. The  anti-inflammatory properties of Hesperetin and Fenugreek further  contribute to overall wellbeing, reducing the risk of chronic  inflammation-related conditions.

• Targeted Male Vitality: By  addressing both hormonal imbalances and supporting physical attributes  like muscle mass and hair health, Alpha Balance provides a holistic  solution for enhancing male vitality and performance.

Conclusion

Alpha  Balance's proprietary formulation combines DIM, Hesperetin, Fenugreek,  Biotin, and BioPerine to create a synergistic blend that effectively  supports hormonal balance, enhances nutrient absorption, and promotes  overall male health. Each ingredient plays a vital role, and their  combined effects provide comprehensive benefits that address multiple  aspects of male vitality and well-being. By integrating these key  ingredients into a daily supplement regimen, men can proactively manage  hormonal imbalances and achieve optimal health and performance.